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Quercetin's Effect on Mitochondial Production & Fatigue

Discussion in 'Latest ME/CFS Research' started by PhoenixBurger, Mar 15, 2013.

  1. alwayshopeful

    alwayshopeful

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    Anyone taking quercetin or calcium?
     
  2. *GG*

    *GG* Senior Member

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    I take calcium via my magnesium supplement, much more magnesium in the supplement than calcium.

    GG
     
  3. Theodore

    Theodore Senior Member

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    Sorry to bump an old thread but how do we know if phase one is already slow? Thx.
     
  4. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    There are labs that test the phases of liver detox but you don't know for sure what is involved in the results. In this case, I had read that quercetin was known to slow down phase one liver detox and assumed that since I had been taking "therapeutic doses" of it for some time, it was likely to have played a part in my very slow phase one results.

    It would be hard to get test results for liver detox when we weren't taking anything (a baseline test), since most of us are taking various things all the time.
     
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  5. Theodore

    Theodore Senior Member

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    Thank you Sushi!
     
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  6. xrayspex

    xrayspex Senior Member

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    u.s.a.
    quercetin is one of the few supps I have taken for many years. I think it helps mitigate slightly histamine responses. I also think though that a side effect is that it increases a certain type of fatigue slightly by maybe lowering my b/p more than it already is.

    I was going to come on and post about it today to see what alternatives are if one has had positive response from it. I thought about nettles but when I have had nettle tea I didn't notice anything great and didnt like it............can't take bromelain or pineapple if that relates.

    I am curious about PPQ you mentioned--what food sources are there and what do you think is best brand of artificial source supp?
     
  7. xrayspex

    xrayspex Senior Member

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    I have been trying calcium again and have thought the d-glucarate form helps energy but its fine line where it crosses over and causes irritability and constipation , neither for which I have much patience for more of................

    I just got some homeopathic cal/fluor because have been having good results from hylands zinc so I thought that might be a back door way in for me with the calcium too.
     
  8. xrayspex

    xrayspex Senior Member

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    on testing I was shown to be slow in phase 2 where things keep circulating too long and causing MCS....is it ok to slow down phase 1 in that situation do you think?
     
  9. ryan31337

    ryan31337 Senior Member

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    Does sound rather typical of MCAS experiences - pruritus and tachycardia probably a reaction to the the adrenal support/LDN and/or fillers in those pills. Quercetin is well known for mast cell stabilising activity, which would in turn reduce mediators like histamine.
     
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  10. CFS_for_19_years

    CFS_for_19_years คภภเє ɠรค๓թєl

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    I think they meant PQQ. This is what I take:
    https://www.amazon.com/PQQ-Mind-Neuroprotective-Cognitive-Support/dp/B00BQS87D2

    The tablets are 20mg. I cut them and take 5mg before noon, never any time after noon, in order to avoid insomnia. If you don't feel any improvement in energy after taking 5mg for 3 days, increase to 10mg for 3 days.

    Some people feel speedy or jittery on this, so be forewarned. I think it may be a matter of getting the dose right.
     
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  11. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    As I remember, several approaches have been used--either trying to speed up phase 2 or slow down phase one. I don't have the information at hand, but if it were me, I'd try to speed up phase 2 to deal with the traffic jam.
     
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  12. Paralee

    Paralee Senior Member

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    A thought, some people can't take PQQ because of a previous fluoroquinolone poisoning, but then others can, I guess it's very individual. I can't.

    Someone mentioned calcium, which I have to take daily with vit. D. Calcium was given a bad rap for a long time but for some people it does help, probably needs some D with it. It also needs to be taken 4 hrs away from magnesium because they use the same receptors.
     
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  13. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    I think it varies a lot with the individual - see https://examine.com/supplements/calcium/ for example.
     
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  14. Paralee

    Paralee Senior Member

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    You're right @MeSci , I had too much calcium, got that fixed, then B6 toxicity pulled my levels down. I also can't take much if any magnesium. Meant to explain everyone is different but phone rang and distracted my focus.

    Of course, that would have been redundant in a way, we all know we're all different.
     
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