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Quercetin and SNPs

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Mindy, Oct 11, 2013.

  1. Mindy

    Mindy

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    Should one avoid Quercetin if they have any particular SNPs? Seems like I read to avoid this early on, but I can't remember where or why. Could've been something else; just not sure, but I'd like to try it to help manage histamine.

    Any input appreciated. Thank you.
  2. Lynn_M

    Lynn_M Senior Member

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    Western Nebraska
    People with COMT snps are recommended to avoid quercetin.
  3. Valentijn

    Valentijn Activity Level: 3

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    Amersfoort, Netherlands
    I'm +/- on two of three COMTs, and haven't had any problem. Is it just an issue for homozygous?
  4. Lynn_M

    Lynn_M Senior Member

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    Western Nebraska
    I've read another person who is heterozygous for at least a couple COMT snps say they had no problem taking quercetin. The place where I read that quercetin is not advised for someone with COMT snps didn't distinguish between homo and hetero. But you might well be correct in thinking it's more of an issue for someone that is homo COMT. Or maybe it depends on the total genome.
  5. Critterina

    Critterina Senior Member

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    Arizona, USA
    I started a few weeks ago using a quercetin supplement, hoping it would help with histamine. I only use it once a day with dinner because it's combined with 1000 mg Vitamin C and I want to keep the C far away from the active Bs I take in the morning. I can't see how it's helped yet. Let me know if you have any luck with it.

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