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Quantitative Assays for Xenotropic Murine Leukemia Virus-Related Virus

Discussion in 'XMRV Research and Replication Studies' started by Bob, Oct 1, 2011.

  1. Bob

    Bob

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    Quantitative Assays for Xenotropic Murine Leukemia Virus-Related Virus

    Sato E, Yoshikawa R, Miyazawa T.

    Laboratory of Signal Transduction, Department of Cell Biology, Institute for Virus Research, Kyoto University.

    J Vet Med Sci

    2011 Sep 30

    http://www.ncbi.nlm.nih.gov/pubmed/21959892

  2. Enid

    Enid Senior Member

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    What is going here Bob for non scientists - XMRV in one moment and out the next - also confusingly referred to as part of the family of HGRVs. Is this as important as it looks ? (interesting connection with PC of which my old Dad with no other family member passed away).
  3. Bob

    Bob

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    I don't understand this abstract either Enid.
    I've only read the abstract, and it looks like they are working on a sensitive XMRV assay.
    But I don't understand why kidney cells or feline cells are involved.
    When the full paper is available, then it might make more sense!
  4. Enid

    Enid Senior Member

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    Thanks Bob - just have wait and see the import of this.
  5. Purple

    Purple Bundle of purpliness

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    It looks like the paper will be published in the Journal of Veterinary Medicine Science / The Japanese Society of Veterinary Science... hopefully it will make more sense later.
  6. Jemal

    Jemal Senior Member

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  7. Esther12

    Esther12 Senior Member

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    Didn't Sato also do one of the negative XMRV/CFS studies? I wonder if they've tried this new testing method on humans yet?
  8. ukxmrv

    ukxmrv Senior Member

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    T Miyazawa was co-author of this poster at a conference a while back.


    5/300(1.7%) of healthy Japanese blood donors positive for antibodies to
    XMRV 'The Prevalence of Xenotropic Murine Leukemia Virus-related Virus in Healthy Blood Donors in Japan'.

    Furuta RA, Miyazawa T, Sugiyama T, Kimura T, Hirayama F, et al.

    Cold Spring Harbor Retrovirus Symposium 2009
  9. Lee

    Lee

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    They have created a tool. They have developed assays that can be used to detect virus if it exists.

    They have not detected virus in humans.

    They say this assay "will be useful for monitoring infectious XMRVs in CFS and PC patients and virological studies for XMRV." That is only true if there are "infectious XMRVs" to detect.

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