Matt_C
Senior Member
- Messages
- 128
- Location
- Sydney, Australia
Hi all,
I was diagnosed with pyroluria last week and so have commenced supplementing with zinc and B6. My doctor recommended I get a "primer pyrrole" capsule for treatment, but as I have the supplements individually i'm going to use those. I have a couple of questions I hope someone with experience with treating pyroluria and methylation can help with.
My GP recommended treating the pyroluria first before methylation. He knows I have already started methylation but he recommended reducing the doses of methylation supplements while I treat the pyroluria. Have others done this? Is it necessary or can I just add the zinc and b6 (and manganese) to my stack? I also take vit e, magnesium and calcium as part of my methylation co-factors.
Some of the "primer pyrole" capsules have differing levels of zinc. Most have 50mg but I’ve seen a reference posted by @ahmo from Klinghardt where 300mg of zinc is recommended. I really have no idea how much zinc I need. My serum level was within range and I’ve seen numerous posts where people do not recommend taking any more than 50 or 100mg, but even warned against 100mg being too much. Any suggestions on how to proceed? I’m guessing a conservative approach of 50mg zinc is probably wise. B6 seems to vary too but the consensus seems to be 50mg p5p and 250-300mg of pyridoxine hcl.
Thanks in advance…
I was diagnosed with pyroluria last week and so have commenced supplementing with zinc and B6. My doctor recommended I get a "primer pyrrole" capsule for treatment, but as I have the supplements individually i'm going to use those. I have a couple of questions I hope someone with experience with treating pyroluria and methylation can help with.
My GP recommended treating the pyroluria first before methylation. He knows I have already started methylation but he recommended reducing the doses of methylation supplements while I treat the pyroluria. Have others done this? Is it necessary or can I just add the zinc and b6 (and manganese) to my stack? I also take vit e, magnesium and calcium as part of my methylation co-factors.
Some of the "primer pyrole" capsules have differing levels of zinc. Most have 50mg but I’ve seen a reference posted by @ahmo from Klinghardt where 300mg of zinc is recommended. I really have no idea how much zinc I need. My serum level was within range and I’ve seen numerous posts where people do not recommend taking any more than 50 or 100mg, but even warned against 100mg being too much. Any suggestions on how to proceed? I’m guessing a conservative approach of 50mg zinc is probably wise. B6 seems to vary too but the consensus seems to be 50mg p5p and 250-300mg of pyridoxine hcl.
Thanks in advance…