I've been saying for years that one of the best ways to do research would be to analyse existing clinical data. There is a vast amount of information - and potential information - in such a resource, if only medics kept good records and if only they were subsequently analysed. It seems so obvious to me. This paper also points out its cost-effectiveness. I'm not sure what they mean by the term 'disruptive' because, as usual, I don't have time to read it through thoroughly. Full text here.