Hormones to repair brain injuries. This caught my eye because I think it's progesterone that may have helped Marly Silverman so much. Interestingly one study found that progesterone metabolites were significantly increased in women with ME/CFS. (?)(Does this mean that progesterone levels were higher or that they were lower (because they were being broken down faster?)_. http://www.endometriosiszone.org/print.asp?page=news_0401_progesterone Progesterone as a neuroprotective factor in traumatic and ischemic brain injury. All of the above in italics may be found in ME/CFS. Could the high progesterone metabolites in ME/CFS be due to these repair processes being initiated. Could they signal damage has occurred?