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Prof. Jonas Blomberg lectures- any questions?

Discussion in 'Latest ME/CFS Research' started by Helen, Mar 27, 2014.

  1. Helen

    Helen Senior Member

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    Hi all,

    Today I recieved an invitation from the ME/CFS group in Gothenburg, to a 2-hour lecture April, 9.
    Prof. Jonas Blomberg will spend two hours with us (a rather small group) explaining his latest study "in layman terms". It was presented here
    http://forums.phoenixrising.me/inde...sh-me-cfs-study-indicates-autoimmunity.26986/

    If you have any questions I will try to get them answered. The study was a bit over my head so I´m looking forward getting a simplified presentation.

    Prof. Blomberg will also talk at the ME conference in London in May
    http://www.investinme.eu/agenda.html#Conference_Programme

    Best
    Helen
     
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  2. natasa778

    natasa778 Senior Member

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    Q:

    wrt his findings, is he aware of research on purinergic antagonist Suramin used to address mitochondrial dysfunction-neuroinflammation, and if he thinks this would be worth pursuing in ME?


    ATP signaling modulates immune responses and chronic inflammation, as well as anti-viral signaling, microglial activation, gut motility and permeability, and sensitivity to food allergens. Suramin inhibits purinergic signaling and has been used for treating African Sleeping Sickness (Trypanosomiasis) since the early 1900s. Treating the offspring of maternal immune activated mice weekly with suramin normalizes their social behavior, motor coordination, body temperature, mitochondrial respiratory function and other metabolic measures. Most impressively, this treatment also corrects a neuropathology ...





    Full paper
     
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  3. natasa778

    natasa778 Senior Member

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    I feel MITOKINES and purinergic signalling is a huge unexplored area in ME, spanning across mito, neuroinflammatory, gut and infection/immune areas and so has a big treatment potential ...


    Thank you!
     
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  4. Helen

    Helen Senior Member

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    Hi @natasa778,

    Thank you for the question and information that sound quite interesting. I hope Prof. Blomberg also finds it worth considering and that I will have a response in some weeks
     
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  5. cigana

    cigana Senior Member

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    Did he ever comment on @natasa778 's question?
     

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