Do any of you have problems with histamine-realeasing foods? If you lack SAMe, your HNMT won't be able to get rid of histamine, resulting in elevated levels intracellularly. Eating these foods will set it free at once, potentially causing symptoms. The symptoms I had each time I consumed: - insomnia (I couldn't sleep for one second) - massive brain fog - weakness - others This should be a good indication for everyone to see if they have enough SAMe. I ate Pumkin seeds today (the worst). Let's see if I can sleep tonight... I'm taking 5-MTHF and am feeling like a million $ since 2 weeks alrdy. I see so few threads concerning this topic even though it is very important imo.