Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
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Probiotic Therapy cured peanut allergy

Discussion in 'Mast Cell Disorders/Mastocytosis' started by ebethc, Aug 17, 2017.

  1. ebethc

    ebethc Senior Member

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    this is a promising result in a therapy that challenges the immune system to find a new & improved homeostasis...

    Published by our friends at the Lancet..


    "...Tang, an immunologist and allergist, pioneered a new form of treatment that combines a probiotic with peanut oral immunotherapy, known as PPOIT. Instead of avoiding the allergen, the treatment is designed to reprogram the immune system’s response to peanuts and eventually develop a tolerance.

    It’s thought that combining the probiotic with the immunotherapy gives the immune system the “nudge” it needs to do this, according to Tang.

    Forty-eight children were enrolled in the PPOIT trial and were randomly given either a combination of the probiotic Lactobacillus rhamnosus with peanut protein in increasing amounts, or a placebo, once daily for 18 months.

    At the end of the original trial in 2013, 82% of children who received the immunotherapy treatment were deemed tolerant to peanuts compared with just 4% in the placebo group.

    Four years later, the majority of the children who gained initial tolerance were still eating peanuts as part of their normal diet and 70% passed a further challenge test to confirm long-term tolerance."
     
    sarah darwins, Mary and Jennifer J like this.

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