This slide presentation by Tiffany Blackden at the 2012 Mastocytosis Society Conference is well worth the read. Her son has been diagnosed with MCAD (aka MCAS), and she is taking a holistic approach to his treatment. I noted that she's addressing improving methylation in her treatment. I have wondered if Rich's theory of lifting the methylation block might dovetail with treating mast cell activation. So sad that he's not around to comment on this. I think he would have found it interesting. Her entire presentation will appear on the 2012 Mastocytosis Society Annual Conference DVDs which the Mastocytosis Society should be releasing soon.