Does anyone else suffer with terrible medication sensitivity as a result of POTS (I suspect I suffer with POTS alone given my symptoms)? I've had to start taking paracetamol for headaches as my old go to, aspirin, gives me the most awful stomach cramps and pain that I cannot take it anymore and even with paracetamol I have to take one tablet divided into two and taken at the start and end of a meal to reduce the stomach side effects. Similarly local anesthesia makes my whole body numb for hours and gives me terrible headaches and sleepiness: I only had a filling done and felt like death for the entirety of that day (although I suspect the stress triggered a hypoglycemia episode which doesn't help matters). Worst of all now is that I seem to react badly to even a mild corticosteroid (1% hydrocortisone) which I have started using on a mild rash that I have on my leg. At first I thought I was flaring for no reason but now I've noticed that whenever I wake up with a headache and terrible muscle pain, it perfectly corresponds to a day where I previously applied the cream. Under normal circumstances I now feel around 70% of my old self but this medication sensitivity is very frustrating to say the least.