Free full text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1114973/ I just read this after seeing another patient quote it. As papers go, it is not that long (4 printed pages). Main section I found of interest: Potential limitations and harms of guidelines. Guidelines are increasingly important in many countries e.g. NICE guidelines in the UK. Guidelines and (so-called) evidence-based medicine are closely linked so people interested in problems with evidence-based medicine might be interested in this.