Forbin
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I thought this was kind of interesting. It's a pretty detailed review of the then current state of knowledge about ME (called here a "post-infectious disease syndrome") from 1988. That's the same year that the CDC created the first "CFS" case definition.
Post-infectious disease syndrome
B. A. Bannister
Postgrad Med J 1988 64: 559-567
http://pmj.bmj.com/content/64/753/559.full.pdf
In addition to a good thumbnail history of the disease as well as a good description of its symptoms (26 years ago), it includes a discussion of the possible role that enteroviruses might play.
Some of the material is dated, I'm sure, but I found this bit intriguing...
If I read that right, he's suggesting that the disease might be the result of exposure to more than one pathogen, perhaps two closely spaced enterovirus exposures, not just one.
I'd imagine that would make the cause much more difficult to pin down since exposure to only one pathogen would be insufficient.
Anyway, it's striking that the disease was being written about with such clarity in 1988... and then they came up with "CFS"...
Post-infectious disease syndrome
B. A. Bannister
Postgrad Med J 1988 64: 559-567
http://pmj.bmj.com/content/64/753/559.full.pdf
In addition to a good thumbnail history of the disease as well as a good description of its symptoms (26 years ago), it includes a discussion of the possible role that enteroviruses might play.
Some of the material is dated, I'm sure, but I found this bit intriguing...
The likely truth is that more than one aetiological agent can be associated with post-viral fatigue. It is even possible that the close association in time of two related infections could modulate the patient's long-term response. Dengue haemorrhagic fever is the effect of consecutive exposures to different dengue virus types; could the experience with polio immunization in Iceland represent a similar behaviour of enteroviruses?
If I read that right, he's suggesting that the disease might be the result of exposure to more than one pathogen, perhaps two closely spaced enterovirus exposures, not just one.
I'd imagine that would make the cause much more difficult to pin down since exposure to only one pathogen would be insufficient.
Anyway, it's striking that the disease was being written about with such clarity in 1988... and then they came up with "CFS"...
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