Phoenix Rising tells QMUL: release the PACE trial data
Mark Berry, Acting CEO of Phoenix Rising, presents the Board of Directors’ open letter to Queen Mary University of London (QMUL) urging them to release the PACE trial data, and hopes that other non-UK organisations will join British charities in the same request...
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Possible Factors of CFS/ME?

Discussion in 'General ME/CFS Discussion' started by Yourmysnowflake, Feb 18, 2013.

  1. Yourmysnowflake



    I'm doing a project at college on CFS/ME as I'm very interested in finding out more due to my mum having the illness.

    I was wondering if there are any possible causes that would be helpful for me to look at? I'm trying to understand more about what might cause the illness and the link with stress.

    I have so far come accross the XMRV link, HPA axis dysfunction and mitochondrial dysfunction. I was also going to look into possible gene markers for CFS/ME so any information on these would be a great help!

    Thank you!:)
  2. taniaaust1

    taniaaust1 Senior Member

    Sth Australia
    Hi the XMRV has been disproven (thou who knows maybe a different kind of virus is involved).

    The HPA axis dysfunction and the mitochondrial dysfunction are both too good areas to research for your article.

    A methylation cycle problem is another possible cause (Rich who's unfortunately not with us any more, used to write a lot about that at this site) and as far as I know there is research being arranged in this area or currently being done. Anyway. here's an article on that by Dr Sarah Myhill is always a good place to do searches for research studies on various things. Here's a start for you (
    A first study of cytokine genomic polymorphisms in CFS: Positive association of TNF-857 and IFNgamma 874 rare alleles.)

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