I agree, I think many of us have a hardwired brain part that responds to authority and its almost impossible to shut it up, particularly an authority in a white coat. The role of cyano B-12 will be a wildcard. Until you lose that, people will not be able to adequately assess you on here to help. Plus you'll have to hear about it every other post. And I agree on the issue of confusion. Over time, if you increase or decrease or add or remove certain supplements you become more aware of what their individual roles are. Potassium -- I had to learn the hard way that food potassium is not enough. You don't want to wait until things get really bad with a potassium deficiency. Methylation creates a potassium sink and that can manifest in many different ways. For me, the potassium deficiency created by methylfolate (or perhaps due to its interaction with B12) causes my feet to be freezing cold at times (I believe this is due to the muscle cramping in my calves impacting the nerves), along with anxiety, dry mouth, sweating at night, muscle pains, exhaustion, etc. Taking potassium directly avoids those effects. I take potassium gluconate powder (Now Foods). Without addressing potassium, it is difficult to know where the tingling/ parethesias / cold extremities are coming from, since a deficiency, I've found, can escalate sensations like that. Since you have a puzzle of a situation, you want to address everything that CAN be addressed easily first. There is likely no irreversible damage.