Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
Discuss the article on the Forums.

positive ANA

Discussion in 'Immunological' started by Omar88, Jun 5, 2017.

  1. Gingergrrl

    Gingergrrl Senior Member

    Messages:
    9,542
    Likes:
    24,651
    USA
    OTH, Even though my ANA pattern was speckled, I am not sure that this factor played any role in my diagnosis or treatment decisions. It must mean something to someone but I still do not understand it to be honest!

    In that case, it might be worth it.

    This is so interesting to me b/c when I saw a rheumy here, he completely dismissed all of my autoantibodies (even though he was a nice man) and would not offer me any treatment. He ran a standard panel (and I was positive for the Hashimoto's antibodies which I already knew) but his panel did not include GAD65, the VGCC antibodies, the cholinergic autoantibodies, etc.

    I had to either do these tests on my own through Cell Trend/Germany or through a Neuro and none are part of a standard rheumy panel here. Once they were all positive, then I started to be taken more seriously but if I had stopped with that Rheumy, it would have been over and I would have been left with the "CFS" diagnosis (which is meaningless in the U.S.).

    But b/c I kept pushing for testing and treatment, I was then able to do a year of IVIG, with another six months of IVIG to go, and soon Rituximab. But that rheumy said my ANA meant nothing and was maybe even a "false positive" which I thought was nonsense b/c all my life I have a negative ANA and now with 11 autoantibodies, I have a positive ANA? The connection seems pretty obvious in my mind!

    Hoping this helps @OverTheHills (and if not it's my random thoughts at midnight here LOL :D)
     
    kangaSue likes this.
  2. sharks

    sharks Senior Member

    Messages:
    137
    Likes:
    117
    Mine was 1:160 speckled in March. After prednisone, 2 weeks of doxy and famvir it went down to 1:80 in May. Everything is normal but the Ana test.
     
    Last edited: Jul 31, 2017
  3. Gingergrrl

    Gingergrrl Senior Member

    Messages:
    9,542
    Likes:
    24,651
    USA
    Does your doctor believe there is a direct correlation between the steroid, doxy and Famvir lowering your ANA or that sometimes the ANA titer can fluctuate on it's own? (I do not know the answer and am just curious what your doctor thinks or how he/she interprets it). Do you notice any change in symptoms with the ANA being lower?
     
  4. TrixieStix

    TrixieStix Senior Member

    Messages:
    531
    Likes:
    879
    Yes I was thinking before that if my blood work my ME/CFS specialist ran showed low NK Cell function that it would make it certain that I have ME/CFS, but after researching low NK Cell function and realizing it's caused by all sorts of conditions I am no longer viewing it as any sort of "proof" that I have ME/CFS.
     
    Last edited: Aug 1, 2017
  5. sharks

    sharks Senior Member

    Messages:
    137
    Likes:
    117
    He thinks it fluctuates on its own. I do notice a difference. I couldn't tell you what worked.
     

See more popular forum discussions.

Share This Page