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Poll: Have you been tested for enteroviruses?

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by halcyon, May 17, 2015.

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Have you been tested for enteroviruses by neutralizing antibodies and/or viral protein tests?

  1. Yes, Coxsackie B antibodies, and I was positive

    11 vote(s)
    29.7%
  2. Yes, echovirus antibodies, and I was positive

    7 vote(s)
    18.9%
  3. Yes, Coxsackie B antibodies, and I was negative

    8 vote(s)
    21.6%
  4. Yes, echovirus antibodies, and I was negative

    2 vote(s)
    5.4%
  5. Yes, I had a VP1 blood (UK) or tissue test (Chia) and I was positive

    4 vote(s)
    10.8%
  6. Yes, I had a VP1 blood (UK) or tissue test (Chia) and I was negative

    0 vote(s)
    0.0%
  7. No, I have not been tested for Coxsackie B antibodies or VP1

    14 vote(s)
    37.8%
  8. No, I have not been tested for echovirus antibodies or VP1

    19 vote(s)
    51.4%
Multiple votes are allowed.
  1. halcyon

    halcyon Senior Member

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    Poll is multiple choice so please choose all that apply to you. A positive antibody titer result is one that the lab flagged as indicative of current or recent infection. Please don't answer yes if your test was negative and done by complement fixation (CF), for example if it was done by Focus Diagnostics in the USA. If you're not sure, post where your test was done and we can try to figure out what method it was.
     
    Valentijn likes this.
  2. Mij

    Mij Senior Member

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    I don't know where this fits in- I had no enterovirus RNA detected.
     
  3. halcyon

    halcyon Senior Member

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    Was this a blood based PCR test?
     
  4. Mij

    Mij Senior Member

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  5. halcyon

    halcyon Senior Member

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    I had thought about putting that in there but the false negative rate for that in chronic infections is so high, much like the CF test. I also figured almost nobody will have had that test but I guess I was wrong on that count. :redface:

    I guess you can select the last two questions then.
     
  6. Mij

    Mij Senior Member

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    I'm under the impression that pcr determines only acute disease.
     
  7. halcyon

    halcyon Senior Member

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    It works best when viremia is occurring yes, during the acute phase of the infection. Dr. Chia tried very hard to locate the virus in the blood with PCR and found it was too unreliable. It's very easy to find in tissue or to find the antibodies in the blood.
     
  8. jstefl

    jstefl Senior Member

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    Brookfield, Wisconsin
    I see I made a mistake. I should have checked the box that says I was positive for a tissue test from Dr. Chia also. My test showed over 50% of the cells were infected.

    John
     
  9. halcyon

    halcyon Senior Member

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    Antibody tests were positive as well though?
     
  10. msf

    msf Senior Member

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    I was also negative for Cocksackie B and Enterovirus by PCR.
     
  11. jstefl

    jstefl Senior Member

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    Brookfield, Wisconsin
    I had my blood tested by ARUP labs and tested positive for two coxsackie and one echo virus.

    John
     

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