Mercury poisoning
Mercury irreversibly inhibits selenium-dependent enzymes and may also inactivate S-adenosyl-methionine, which is necessary for catecholamine
catabolism by
catechol-o-methyl transferase. <--The COMT Problem.
Affected children may show red
cheeks,
nose and lips, loss of
hair,
teeth, and
nails, transient rashes,
hypotonia (muscle weakness), and increased sensitivity to light. Other symptoms may include
kidney dysfunction
(e.g. Fanconi syndrome) or neuropsychiatric symptoms such as emotional
lability,
memory impairment, and / or
insomnia.
Mercury is unique among the heavy metals in that it can exist in several physical and chemical forms, including elemental mercury, which is a liquid at room temperature. All forms of mercury have toxic effects in a number of organs, especially in the kidneys. Within the kidney, the pars recta of the proximal tubule is the most vulnerable segment of the nephron to the toxic effects of mercury. The biological and toxicological activity of mercurous and mercuric ions in the kidney can be defined largely by the molecular interactions that occur at critical nucleophilic sites in and around target cells. Because of the high bonding affinity between mercury and sulfur, there is particular interest in the interactions that occur between mercuric ions and the thiol group(s) of proteins, peptides and amino acids. Molecular interactions with sulfhydryl groups in molecules of albumin, metallothionein, glutathione, and cysteine have been implicated in mechanisms involved in the proximal tubular uptake, accumulation, transport, and toxicity of mercuric ions. In addition, the susceptibility of target cells in the kidneys to the injurious effects of mercury is modified by a number of intracellular and extracellular factors relating to several thiol-containing molecules.
Smoking Teeth / Poison Gas
Trace minerals are essential for all of us. Besides their vital role in the health of our metabolism, they seem to be able to relocate heavy metals by mobilizing them and keeping them moving, eventually fining them an exit door. Listening to Ed Kane describe the process with BodyBio Liquid Minerals is not only interesting, but seems the only safe and healthy way to get the job done.
BodyBio Video Library - Trace Minerals Video Part One
http://www.bodybio.com/content.aspx?page=BodyBioWellnessVideoLibrary
Molecular interactions with mercury in the kidney
http://www.ncbi.nlm.nih.gov/pubmed/10699157
Mercury poisoning Wiki
http://en.wikipedia.org/wiki/Mercury_poisoning