A New Decade of ME Research: The 11th Invest in ME International ME Conference 2016
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Please help me get diagnosed!

Discussion in 'Genetic Testing and SNPs' started by AspireApex, Oct 12, 2015.

  1. AspireApex

    AspireApex

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    Hello,
    Recently diagnosed with ME/CFS - I have posted my genetic genie results. What can I do to start support my MFTHR in terms of medications and supplements. Complete noob here!
     

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  2. Valentijn

    Valentijn Senior Member

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    Methylation SNPs aren't a basis for diagnosing anything. And even if it were, we aren't doctors and you aren't our patient, so we couldn't diagnose you anyhow :p

    MTHFR C677T +/- means that you convert folic acid into active folate at about 65% of the optimum rate. But because MTHFR mutations are extremely common, that means yours is pretty average. At most it indicates that eating a decent amount of veggies or supplementing a normal dose of methylfolate (such as is found in a typical multivitamin) might help in keeping homocysteine levels in normal range.
     
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  3. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

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    @AspireApex

    In a nutshell -- your genetic mutations to not look severe. Perhaps your ME/CFs may be caused by something else (infections, mitochondrial damage, subclinical thyroid problem, adrenal issues, toxins, parasites, etc).

    MAO A R297R - is best supported with adequate B2 intake and a fully functioning thyroid.
    VDR taq - make sure your Vitamin D levels are adequate - test to make sure your Vitamin D levels are in range, supplement if low
     
  4. caledonia

    caledonia

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    Cincinnati, OH, USA
    @AspireApex Can you post your Detox Profile results too?
     
  5. AspireApex

    AspireApex

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    Here is my detox profile!
     

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  6. AspireApex

    AspireApex

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    With the MTHFS mutation, it seems as though I should avoid all sources of folate that are not methylfolate. Does this sound correct? My symptoms all started after I started eating more spinach/broccoli and olive oil on a regular basis. Assuming I refrain from eating these, will my methylation status slowly revert back to normal assuming I stay away from all folinic acid? What are your experiences?
     

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