Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Please help me get diagnosed!

Discussion in 'Genetic Testing and SNPs' started by AspireApex, Oct 12, 2015.

  1. AspireApex

    AspireApex

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    Hello,
    Recently diagnosed with ME/CFS - I have posted my genetic genie results. What can I do to start support my MFTHR in terms of medications and supplements. Complete noob here!
     

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  2. Valentijn

    Valentijn The Diabolic Logic

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    Methylation SNPs aren't a basis for diagnosing anything. And even if it were, we aren't doctors and you aren't our patient, so we couldn't diagnose you anyhow :p

    MTHFR C677T +/- means that you convert folic acid into active folate at about 65% of the optimum rate. But because MTHFR mutations are extremely common, that means yours is pretty average. At most it indicates that eating a decent amount of veggies or supplementing a normal dose of methylfolate (such as is found in a typical multivitamin) might help in keeping homocysteine levels in normal range.
     
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  3. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

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    @AspireApex

    In a nutshell -- your genetic mutations to not look severe. Perhaps your ME/CFs may be caused by something else (infections, mitochondrial damage, subclinical thyroid problem, adrenal issues, toxins, parasites, etc).

    MAO A R297R - is best supported with adequate B2 intake and a fully functioning thyroid.
    VDR taq - make sure your Vitamin D levels are adequate - test to make sure your Vitamin D levels are in range, supplement if low
     
  4. caledonia

    caledonia

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    Cincinnati, OH, USA
    @AspireApex Can you post your Detox Profile results too?
     
  5. AspireApex

    AspireApex

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    Here is my detox profile!
     

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  6. AspireApex

    AspireApex

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    With the MTHFS mutation, it seems as though I should avoid all sources of folate that are not methylfolate. Does this sound correct? My symptoms all started after I started eating more spinach/broccoli and olive oil on a regular basis. Assuming I refrain from eating these, will my methylation status slowly revert back to normal assuming I stay away from all folinic acid? What are your experiences?
     

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