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Personality Features and Personality Disorders in Chronic Fatigue Syndrome: A Populat

Discussion in 'Latest ME/CFS Research' started by V99, Jul 28, 2010.

  1. oceanblue

    oceanblue Senior Member

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    I know, it's so frustrating. Sometimes, I fantasise:
    --- fantasy fades......

    Well, it makes me feel better.

    The whole of idea of scientific publication is built around Peer Review, where your work is scrutinised by your peers before it is accepted for publication. In many fields this can be a bloody process, with researchers trying to undermine their rival's papers with hostile reviews. But the results is fierce scrutiny and better quality work. In the field of ME/CFS, peer review seems to be no more than a slap on the back from your mates.

    The reality is that nothing will change and research like this will continue to be published. It makes me want to weep.
     
  2. Dolphin

    Dolphin Senior Member

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    Great analysis, oceanblue. And humour is always welcome! :Retro smile:
     
  3. BEG

    BEG Senior Member

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    "Discussion:
    Our results suggest that CFS is
    associated with increased prevalence of maladaptive personality
    features and PDs.

    It might be assumed that these persons are more
    likely to be non-compliant to treatment suggestions, display unhealthy
    behavioral strategies, and lack a stable social environment.

    The question arises whether personality dispositions are a premorbid risk
    factor or whether they are a consequence of the chronicity and severity
    of CFS."


    Reeves and the CDC give me a big PD. That's a personality disposition characterized by venemous, embroiling, scorching rage. Premorbid? Hah! It was cultivated over the years by inane idiots at the CDC, masquerading as scientists. As I lose day after day to the walking death syndrome, this PD grows exponentially as the CDC becomes dumber (their own PD.) The question arises whether their PD is a risk factor for researching CFS or a consequence of conducting their insane research.

    In any case, Reeves is a sick man with a maladaptive personality feature, a reluctance to accept true science. I believe his friends at Emory should help him before his PD diminishes his capacity to function even in his own little world.
     
  4. oceanblue

    oceanblue Senior Member

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    Hey, delighted you liked the analysis! The piece was really just a bit of therapy for me (and I feel much better for it).
     
  5. Dolphin

    Dolphin Senior Member

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    She has sent it on now so no inordinate delay.
     
  6. SOC

    SOC Senior Member

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    Thanks for the new fantasy! :D

    I do wonder who the heck is "peer-reviewing" and approving this BS. It really brings Retrovirology's scientific ethics into question, IMO.
     
  7. Dolphin

    Dolphin Senior Member

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    I have just taken a quick look at the table of correlations between the eight SF-36 and the 5 personality features and also the five MFI20 subscales and the five personality features.
    One very clear that thing is that the personality features are associated with poor health/quality of life/fatigue in all of the three groups. For the CFS group, there are 28 out of a possible 65 statistically significant correlations. The figures for ISF and the control group are 43 (!) and 25.

    If one breaks down into the five personality factors, across the three groups there are the following number of correlations:
    Column 1: Neuroticism: 27 correlations (out of a possible 39)!
    Column 2: Extraversion: 26 correlations (out of a possible 39)
    Column 3: Openness: 9 correlations (out of a possible 39)
    Column 4: Agreeableness: 12 correlations (out of a possible 39)
    Column 5: Conscientiousness: 22 correlations (out of a possible 39).

    So in total 96 out of a possible 195.
    It was by chance, it would be 9.75. I'm sure this is statistically significant.

    Note: higher SF-36 subscale scores (first eight) equals more function/better quality of life. Higher MFI20 subscale scores (last five) equals worse fatigue and the like. Positive correlations mean as one goes up, the other goes up also. Negative correlations mean, as one goes up, the other gets lower.

    Chronic Fatigue Syndrome (CFS), Persons with Insufficient Symptoms or Fatigue (ISF) and Well Controls (Well)
    CFS
    Neuroticism Extraversion Openness Agreeableness Conscientiousness
    Physical Functioning -.017 .023 .109 -.094 .034
    Role Physical -.052 .125 -.026 -.163 -.013
    Bodily Pain .060 .004 .062 -.078 -.113
    General Health -.162 .128 .149 -.029 .152
    Vitality -.384(**) .334(**) .126 -.084 .089
    Social Functioning -.419(**) .349(**) .241(*) .062 .200(*)
    Role Emotional -.564(**) .361(**) .310(**) .220(*) .211(*)
    Mental Health -.731(**) .469(**) .327(**) .318(**) .371(**)
    General Fatigue .240(*) -.150 -.041 .182 -.070
    Physical Fatigue .125 -.085 -.051 .165 .015
    Reduced Activity .180 -.223(*) -.201(*) .020 -.275(**)
    Reduced Motivation .405(**) -.394(**) -.204(*) -.057 -.333(**)
    Mental Fatigue .503(**) -.284(**) -.190(*) -.011 -.500(**)

    ** Correlation is significant at the 0.01 level (2-tailed).
    * Correlation is significant at the 0.05 level (2-tailed).


    ISF
    Neuroticism Extraversion Openness Agreeableness Conscientiousness
    Physical Functioning -.172(**) .299(**) .112 .076 .150(*)
    Role Physical -.056 .141(*) .110 .125(*) .059
    Bodily Pain -.105 .133(*) .057 .158(*) -.034
    General Health -.351(**) .338(**) .113 .202(**) .199(**)
    Vitality -.442(**) .436(**) .052 .113 .247(**)
    Social Functioning -.362(**) .249(**) .068 .170(**) .110
    Role Emotional -.364(**) .219(**) -.041 .193(**) .165(**)
    Mental Health -.679(**) .375(**) .061 .200(**) .252(**)
    General Fatigue .353(**) -.313(**) -.040 -.088 -.193(**)
    Physical Fatigue .259(**) -.320(**) .001 -.096 -.235(**)
    Reduced Activity .219(**) -.462(**) -.071 -.053 -.336(**)
    Reduced Motivation .375(**) -.512(**) -.122(*) -.140(*) -.414(**)
    Mental Fatigue .442(**) -.225(**) -.008 -.197(**) -.288(**)

    ** Correlation is significant at the 0.01 level (2-tailed).
    * Correlation is significant at the 0.05 level (2-tailed).



    Well
    Neuroticism Extraversion Openness Agreeableness Conscientiousness
    Physical Functioning -.279(**) .094 .186(*) -.014 .010
    Role Physical -.168 .166 -.075 .177(*) .133
    Bodily Pain -.192(*) .131 .070 .090 .045
    General Health -.266(**) .237(**) .090 .062 .187(*)
    Vitality -.298(**) .197(*) -.072 .067 .250(**)
    Social Functioning -.165 .118 -.176 .196(*) .021
    Role Emotional -.118 .222(*) -.194(*) .162 .091
    Mental Health -.454(**) .190(*) -.134 .087 .136
    General Fatigue .276(**) -.055 .056 .037 -.146
    Physical Fatigue .248(**) -.128 .000 -.011 -.257(**)
    Reduced Activity .168 -.265(**) .009 -.030 -.314(**)
    Reduced Motivation .283(**) -.306(**) -.133 -.157 -.339(**)
    Mental Fatigue .362(**) -.103 .022 .007 -.262(**)

    ** Correlation is significant at the 0.01 level (2-tailed).
    * Correlation is significant at the 0.05 level (2-tailed).
     
  8. Dolphin

    Dolphin Senior Member

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    He's certainly might be uncomfortable with many people reading that table - it pretty much means that one can't read anything into the personality features data.

    It would be very interesting if they prepared and presented a similar table of correlations with the personality disorders. My guess is that they did prepare at as all the data is in the computer. We're just not getting to know what they found.
     
  9. Hope123

    Hope123 Senior Member

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  10. oceanblue

    oceanblue Senior Member

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    You've clearly been very busy well into the night! A hugely impressive effort to gather this additional data and analyze it. You said:

    Could you expand on this a bit? Some of us are a bit mesmerized by so much data. Are you effectively saying you could draw a huge number of different conclusions from the data, depending on what you wanted to highlight, or that nothing is significant at all? It seems to me that you are saying something very important about the validity of the reserach, but I haven't quite grasped it.

    Thanks
     
  11. Dolphin

    Dolphin Senior Member

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    Thanks Oceanblue.
    They ran two sets of tests relating to personality.

    If one looks at the table above, one can see that for the personality features test, what one sees for all the groups (CFS, ISF and controls) is that the scores on the personality features test correlate with a lot of scores on the quality of life and fatigue measures. This could be said to mean that nothing CFS-specific has been found - all, in a way, one is doing when one measures neuroticism or whatever is measuring quality of life/fatigue rather than a separate independent marker. There is the possibility the direction of causation is the other way of course and the personality features cause the lower scoring. But it is the case across the three groups and it not clear how plausible that would be, across society, for extraversion for example.

    Of course, the main issue in the study is the Personality Disorders data. There is no mention of them looking at whether there are any correlations between it and the SF-36 and MFI20 subscales - if it did find the same sorts of correlations (which they could do easily with the data in the computer), it would again suggest the researchers didn't find anything interesting. Perhaps such data exists from other research, I don't know.
     
  12. oceanblue

    oceanblue Senior Member

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    So, they found nothing that links personality traits specifically to CFS, at least not causally, not even neuroticism. Shame they didn't put this in the abstract. The table of data you extracted from them relly does reinforce the 'so-whatness' of their findings. I guess that's why they left it out.
     
  13. Tammie

    Tammie Senior Member

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    looking this over, I noticed something else that could easily skew the tests........there are a lot of "reverse" questions, and I have read elsewhere that people with cognitive difficulties have a hard time processing these questions properly and as a result answer them backwards to what they really mean

    for exp, here are some sample questions:

    "Sample openness items

    * I have a rich vocabulary.
    * I have a vivid imagination.
    * I have excellent ideas.
    * I spend time reflecting on things.
    * I use difficult words.
    * I am not interested in abstractions. (reversed)
    * I do not have a good imagination. (reversed)
    * I have difficulty understanding abstract ideas. (reversed)"

    Though these may look obvious to a lot of people, it has been shown that when someone with cognitive difficulties reads questions like this, they sort of miss the way that the questions flip from "I am" to "I am not" and they cont to answer them as they would if all the questions said, "I am". Obviously this will not give accurate results!

    and then there are these:

    "Sample conscientiousness items

    * I am always prepared.
    * I am exacting in my work.
    * I follow a schedule.
    * I get chores done right away.
    * I pay attention to details.
    * I leave my belongings around. (reversed)
    * I often forget to put things back in their proper place. (reversed)
    * I shirk my duties. (reversed)"

    Even if interpreted properly, it is not hard to understand why someone sick with ME/CFS might answer these in a way that would indicate (in a healthy person) a lack of conscientiousness, but in us just indicates we are too darn sick to do some of these things!

    And still some more,

    "Sample extroversion items

    * I am the life of the party.
    * I don't mind being the center of attention.
    * I feel comfortable around people.
    * I start conversations.
    * I talk to a lot of different people at parties.
    * I am quiet around strangers. (reversed)
    * I don't like to draw attention to myself. (reversed)
    * I don't talk a lot. (reversed)
    * I have little to say. (reversed)"

    yeah, us ME/CFS peeps have the energy to be the life of the party, and if we are not, it must mean we are introverted! :rolleyes:and the rest can be issues due to cognitive problems, fatigue, etc, and once again say absolutely nothing about how introverted/extroverted we are
     
  14. Snow Leopard

    Snow Leopard Senior Member

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    Besides the unreliability of questionnaires, the problem with these sorts of studies is often selection bias - out of those who have CFS, those who have certain personality types might simply be more likely to participate in such studies. Unfortunately, this possibility seems to be rarely examined or even discussed in this sort of research.

    Of course I don't have access to this article and most of that 29% might just have depression. ;)
     
  15. Dolphin

    Dolphin Senior Member

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    I think that is a bigger criticism of all the other studies than have been done than this one. This was only a small part of testing they did (for three days?). And people were selected from by random digit phoning.

    This is certainly a possibility given it uses the empiric criteria (Reeves et al, 2005). But we are not given information on the individuals. And it will probably appear to most readers that the Fukuda criteria was used and this is a good random selection of CFS patients.
     
  16. Enid

    Enid Senior Member

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    Quite agree CFS so called is simply one aspect of the severe pathologies now known. All illnesses produce fatigue as does ME. About time Myalgic Encephelomyalitis was reinstated.
     
  17. Dolphin

    Dolphin Senior Member

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    I forgot to say that we know information about the cohort of CFS patients in general (but not which have personality disorders etc) from other studies e.g.
    http://www.ncbi.nlm.nih.gov/pubmed/19414619

     
  18. justinreilly

    justinreilly Stop the IoM & P2P! Adopt CCC!

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    I agree that now casting us as having personality disorders is very smart since pwPD generally have 'defective', amoral or immoral characters- they are generally narcissistic, manipulative, irrational, abusive and always think they are right and anyone who opposes them are wrong no matter the evidence. This is perfect for them to allege since they can say 'these people are manipulative and will never take responsibility for their own laziness and craziness so they try to blame us innocent CDC scientists.'

    finally?????? It's clear to me and almost everyone else who's been following CDC that they've been this bad and waging a PR war on ME patients and science since day one. Just to cite two example out of scores:

    -remember the fact that the misappropriated at least tens of millions of dollars from the "CFS" budget from the beginning until 1999- in most years almost the entire "CFS" budget- and lied in their testimony to Congress year-in and year-out about it.

    -remember the "Dear Sirs, I am sick" joke letter they had up on their community bulletin board for a year and a half until Hillary Johnson saw it with the hysterical "CFS" patient saying "the [antipsychotics] only work when I take them."

    Cort, Please don't give cover to these criminals by suggesting that they have been mostly trying their best (as you said in your blog post) and that only very recently have they gotten really bad. IMO this is a huge disservice to ME patients.
     
  19. justinreilly

    justinreilly Stop the IoM & P2P! Adopt CCC!

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    Notice how biased these people are. Why does the same rate of Axis II disorders in normals and ME patients "suggest only a minor etiological role for personality pathology, as defined by the DSM-IV Axis II, within CFS"? It obviously suggests NO etiological role for personality disorders, not "a minor role."

    It never ceases to amaze me what anti-science garbage on ME gets published.
     
  20. justinreilly

    justinreilly Stop the IoM & P2P! Adopt CCC!

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    Ha! I'd like insufficient fatigue and 'chronic unwellness'. Sounds like a blast compared to the hell of ME.
     

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