Pentosan polysulfate sodium

[kangaSue]

There was an interesting article in my local weekend paper (Q Weekend Magazine; Don't let the bugs bite) about the re-use of an old drug, pentosan polysulfate sodium (PPS), as a treatment for the debilitating fatigue and joint pains that are hard to treat in Ross River Virus.

The Virologist, who also had the virus herself, was looking for any novel anti-inflammatory, antiviral combination drug to try and found that the 50 y.o.drug, used orally in Interstitial Cystitis, was remarkably effective for these symptoms in some patients in doing preclinical trials into the drug as an injection.

 

[Hip]

pentosan polysulfate sodium (PPS), as a treatment for the debilitating fatigue and joint pains that are hard to treat in Ross River Virus.

Ross River Virus is associated with ME/CFS, so perhaps pentosan polysulfate (Elmiron) will help other forms of ME/CFS.



It's interesting that pentosan polysulfate helps repair the damaged protective glycosaminoglycan layer (GAG layer) in the bladder, which is how it is thought to help interstitial cystitis and overactive bladder.

I just wrote this post which details how you can repair the bladder GAG layer in interstitial cystitis and overactive bladder, and I have now added pentosan polysulfate to this.

Another way to repair the bladder GAG layer is to instill into the empty bladder may be to use a solution of chondroitin sulphate (Gepan and Uracyst are two such chondroitin sulphate products employed for this purpose).


A damaged bladder GAG layer may allow toxins that are excreted into the urine to re-enter the body.

 

[kangaSue]

Ross River Virus is associated with ME/CFS, so perhaps pentosan polysulfate (Elmiron) will help other forms of ME/CFS.

Yes, that was my thinking in posting this. I didn't realize I left out the paragraph in reference to ME/CFS in cutting and pasting this in a hurry.

The real intent of the post was that, while it was not stipulated specifically in the article, I gather that giving PPS as an injection was more effective than taking it orally.

 

[frozenborderline]

Ross River Virus is associated with ME/CFS, so perhaps pentosan polysulfate (Elmiron) will help other forms of ME/CFS.



It's interesting that pentosan polysulfate helps repair the damaged protective glycosaminoglycan layer (GAG layer) in the bladder, which is how it is thought to help interstitial cystitis and overactive bladder.

I just wrote this post which details how you can repair the bladder GAG layer in interstitial cystitis and overactive bladder, and I have now added pentosan polysulfate to this.

Another way to repair the bladder GAG layer is to instill into the empty bladder may be to use a solution of chondroitin sulphate (Gepan and Uracyst are two such chondroitin sulphate products employed for this purpose).


A damaged bladder GAG layer may allow toxins that are excreted into the urine to re-enter the body.

What are the main side effects of elmiron I am dealt worried it will cause irreversible balding. I'm being offered it to help with my bladder irritation from ketamine

 

[frozenborderline]

Also does it have much documented benefits beyond bladder repair ? As in helping with systemic disease

 

[frozenborderline]

Ross River Virus is associated with ME/CFS, so perhaps pentosan polysulfate (Elmiron) will help other forms of ME/CFS.



It's interesting that pentosan polysulfate helps repair the damaged protective glycosaminoglycan layer (GAG layer) in the bladder, which is how it is thought to help interstitial cystitis and overactive bladder.

I just wrote this post which details how you can repair the bladder GAG layer in interstitial cystitis and overactive bladder, and I have now added pentosan polysulfate to this.

Another way to repair the bladder GAG layer is to instill into the empty bladder may be to use a solution of chondroitin sulphate (Gepan and Uracyst are two such chondroitin sulphate products employed for this purpose).


A damaged bladder GAG layer may allow toxins that are excreted into the urine to re-enter the body.

Hey hip, what do you know about the statistics on elmiron safety and the main side effects. Does it cause pattern baldness or blindness? Stats are good for me, bc just lists of side effects are meaningless , often rare side effects listed right next to common, impossible to tell

 

[Hip]

what do you know about the statistics on elmiron safety and the main side effects

FOund this page detailing side effects.

This is how side effects are classified in terms of how likely they are:

Very common, ≥ 1⁄10
Common (frequent), 1⁄100 to 1⁄10
Uncommon (infrequent), 1⁄1000 to 1⁄100
Rare, 1⁄10000 to 1⁄1000
Very rare, < 1⁄10000

https://en.wikipedia.org/wiki/Side_effect

 

[frozenborderline]

FOund this page detailing side effects.

This is how side effects are classified in terms of how likely they are:

Very common, ≥ 1⁄10
Common (frequent), 1⁄100 to 1⁄10
Uncommon (infrequent), 1⁄1000 to 1⁄100
Rare, 1⁄10000 to 1⁄1000
Very rare, < 1⁄10000

https://en.wikipedia.org/wiki/Side_effect

Thanks. See this @rpapen77