In 2006 the UK Parliament Group on Scientific Research in ME (the Gibson Inquiry) held a series of public hearings to assess the progress (or lack) of ME research. This was a particularly interesting process because it included investigating the political and social environment we find ourselves stuck in. To me, it was what the "P2P" could have been if it had been convened by honest people. A group called "BRAME - Blue Ribbon for the Awareness of Myalgic Encephalomyelitis" submitted a review of important research papers, including Dr Peckerman's 2003 paper "Abnormal Impedance Cardiography Predicts Symptom Severity in CFS". I have posted the review of the paper in it's entirety, so it's rather lengthy. I've been thinking about this paper while reading about recent research by Fluge and Mella into endothelial dysfunction. I'm not qualified to analyze research papers, so I am very curious to find out if this paper has stood the test of time. Has there been any follow up at all in the past 12 years? Should there be? Does anyone know off hand if this research was included in either the P2P or the IOM evidence reviews? I vaguely recall that the P2P evidence review only included treatment trials. Apparently treatment does not require diagnosis.