Probably this has been addressed before but lets see what happens... http://beverlyhillsshrink.blogspot.com.es/2012/03/adult-pandas-bare-facts.html According to this guy, not only streptococcal infections but also Lyme and a bunch of other infectious agents CAN precipitate an "adult PANDAS" (which would be ANDAS, no, it would be ANDACI: Autoimmune Neurological Disorder Associated with Chronic Infections). The guy says chronic infections cascading autoimmunity "nest" in the GUT, sinuses, tonsils and some more. I am going to test my ASLO and Anti-DNase B and if possible some more. This is to be taken into consideration as well: http://www.sciencedirect.com/science/article/pii/S0091674904001927 In any case elevated ASLO/ASO might be a marker of autoimmunity in cases of chronic "mysterious", "somatic" or "psychiatric" health problems. Really intriguing!! I got prompted to review this before some guy on another chronic health problems forum came saying he was desperate after years of illness and he curiously had elevated ASLO which he assures remains a constant in test results. I am positive HE has "ANDAS", not so sure about me, since I had this clear mental picture of what started my autoimmunity, but is worth a shot since I do hace OCD and apparently everyone in my house is sick at this point.