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Nitric oxide and its possible implication in ME/CFS (Part 2 of 2)
Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. This second article in a 2-Part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS....
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Pall peroxy nitrite treatment failure

Discussion in 'General Treatment' started by vortex, May 20, 2014.

  1. vortex

    vortex

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    I got my methylation panel back and my nitrotyrosine levels were elevated.
    So I read up on pall theory that nitrotyrosine is linked to peroxynitrite and
    That can be at the core of this cfs disease.

    So I researched and followed the protocol to try to lower peroxynitrite levels
    Using gamma e tocopherol and tocotrienol, but 2 or 3 days in I got sick with
    A lung infection that never went away, so I took antibiotics to cure.

    I wasn't sure if there was a connection or it was random, so I read up
    On the protocol and tried something else, so I found hydroxocobalamin
    Is a powerful scavenger of peroxynitrite or nitric oxide etc. so I did 10mg

    Injections and within 2-3 days now I have a bad cold.
    So now I am looking for a reason why suppressing peroxynitrite is causing
    Immune system suppression.

    I have read that the immune system uses peroxynitrite to fight infections
    So maybe because I have hhv6 ebv, mycoplasma etc that my nitrotyrosine
    Levels are elevated because my immune system is trying to kill these infections.
    Which baffles me because from everything I have read, the pall theory is that
    Elevated peroxynitrite is causing all my problems, and leads to these infections.

    So I am stuck now on what to do now. I am researching while I recover from
    This cold.

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