Thank you all so much for all your input.......it is genuinely much valued! The extent of all your pain & symptoms is just horrendous.......and I sincerely hope that this site, Phoenix Rising, is able to help you at least share what you're going through and offer you hope & possible remedies. I learned today that my particular leg pain is more likely to be associated with my newly-diagnosed Osteoarthritis.......so that's that sorted. And as I've been on the same meds long enough to know they're not the culprit, is it my heart issues/exertion that causes the fatigue........or cfs? The jury's still out on that one, but I'm determined to do all I can to try & understand what's going on. And the very best to all of you as well!