I thought I would start a thread for letters in reply to the PACE Trial that were not accepted by the Lancet. It might act as a sort of summary of some observations people made. People can PM their letters if they prefer (I can include it either with or without their name - it doesn't matter to me). Best to keep comments on letters to another thread (you can link to the posts) I think. ETA: There are now 30 letters from 25 people/groups in this thread.