Discussion in 'Gastrointestinal and Urinary' started by Asklipia, Jun 6, 2015.
I have added a new thread with my latest discoveries!
Interesting take on oxalates (apart from the raw-foodism advertisement):
I found a variant in my gene report yesterday that showed I might be susceptible to oxalates. I hope I saved it or printed it out....time to get organized.
Pls share & consider posting on trying low oxolates facebook group
@aquariusgirl , who were posting to?
@aquariusgirl , ok, that's what I thought, but sometimes I answer someone's question to someone else as if it were to me, so wanted to make sure.
I will look for what I found, papers scattered everywhere. I'm a member over there so I was going to make sure I understood it right before I started scattering the wrong info.
Here's what I found and I'm homozygous. It's gene SLC13A1 and the allele (?) is rs7780966. This is just what I found as one of my variants and it says it (the gene) can cause osteochondrodysplasia and hyperoxyluria. I don't know if it's with this particular snp or not.
I can only get so far trying to track things down and then I finally give up because I don't know how to figure the fine points out. I did find some articles to confirm the snp but I'm not sure if this type of oxyluria is what I was looking for.
Maybe? Wish I could get a better handle on figuring this stuff out.
Anyway, if anyone knows anything about it, I would need to know before I say any more, because it's like hit or miss with me. thanks.
I don't see any indication that that particular SNP has any impact. Also, both alleles are extremely common, so a great many people (20-25%) would be homozygous for either version.
Thanks Valetijin, I did notice they were both common, one of these days I'll be able to learn about individual snps better, maybe.
After a recent adverse event I am thanking my eye improvement to the milk riboflavin. And the worsening to excess boron / sulfites which deplete B2.
@Gondwanaland or someone that knows about buying the B2 and K2 supplements.....What brand would be good and how much should I take? (I'm sensitive with supplements).
I was reading about this and I think now I'm low on B2 because of the skeletal problems a deficiency can cause, and I've been meaning to get the K2. I almost bought it once but it had the mk4 and mk7 in equal amounts. I wasn't sure if that was good or a different percentage would be better.
I seem to have deficiencies in boron also, so maybe a small amt of boron and B6 (yes, now I'm low in
B6) so.....thanks if you know. I'm wondering if they would just all end up cancelling each other out?
@Paralee I mostly order my supps from a local compounding pharmacy, but when I buy online my personal criteria to choose supplements are:
1) it must be affordable
2) I prefer in capsules so I can open them and pour just a tiny bit in a glass with water to gauge my reaction and find out what they do (tablets can be hard to cut)
3) I always pick the lowest dosage available
4) I avoid brands that use multiple unpronounceable fillings
Other people have other criteria
Thanks @Gondwanaland , I hadn't thought of a compounding pharmacy, much preferable than all that filler junk. I will call and see what they are willing to do.
@Gondwanaland , I think I may need to build my vit. D back up a little first before I try the K2, as per a post I just saw on possibly needing calcium supplements that you posted. I've been a little lax on my vit. D intake, and calcium won't absorb without the D, or so I've heard.
Blood results of vitamins D2 and D3 are useful in this instance.
@Gondwanaland , my vit d2 is always low and vit D3 isn't much better unless I really take it every day, and then it tests barely normal. I've slacked off considerably, so I know I need them. What I'm wondering about is the vit. B2.....try and get that tested, lol. Dr. didn't even check my folate when I asked. So I'm hoping just a small amount of B2 would be ok to try to see if it helps with my leg pain (& other areas). It feels like my leg is trying to break right under my right knee.
Poor Zinc metabolism involved in oxalate kidney stones. This is why B6 (and carnosine/carcinine) helps... Click the link for related published research at the bottom of the page. Bolding mine.
@Asklipia @aquariusgirl @prioris @Violeta @picante @Lolinda
Interestingly, a lower Zinc intake correlates with increased risk for kidney stones in humans:
You can also try a Google Site Search
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