Hi folks, this is my first post. I came down with CFS in 1991. It hit hard, I was in bed for the first year and a half. It took my career, house, family and marriage. It has been a long road of a roller coaster ride which has precluded participation in most aspects of my former life. In the 10 years before CFS I had IBS or whatever it is, with killer diarrhea. Just before the CFS I got onto cholestyramine which has worked pretty well. About 8 months ago I developed intense stomach pain. Bad enough that I went to emergency three times. I have had an ultrasound, cat scan, mri, colonoscopy, gastroscopy, all to no avail. I am on oxycodone and oxycontin for the pain and the drug is making life even more difficult. Along with the pain I experience intense nausea, I vomit frequently and have lost thirty pounds. The oxy causes bad constipation which breaks every four or five days with extremely painful cramps and diarrhea, then the cycle begins again. I am writing this to ask if any of you has had/is having a similar g.i. problem, because I am beginning to get pretty damn depressed with it all and can see no light at the end of the tunnel. A great telephone friend of mine with ME says she believes it will resolve itself one day, and I am really hoping that some of you can corroborate this, as I think you can imagine what this level of pain and sickness together with the oxy is doing to my CFS/ME. I, like most with this disease, have seen many doctors and been met with shrugged shoulders more times than any human should have to put up with, and I'm now getting the same routine with this belly pain. FWIW, I'm 60, male and tolerably well-educated. Any info/help out there?