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ME/CFS: A disease at war with itself
We can all agree that ME/CFS is a nasty disease, particularly in its severe form, but there are abundant nasty diseases in the world. What is unique and particularly confounding about our disease is that so much controversy surrounds it, and not only surrounds it, but invades it too.
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Our "fatigue"

Discussion in 'Post-Exertional Malaise, Fatigue, and Crashes' started by SaveMe, Apr 20, 2011.

  1. SaveMe

    SaveMe *****

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    the city
    drained, depleted, wiped out, exhausted.

    Suppression of a virus/retrovirus will not correct the issue.

    I feel the damage done is on a cellular level involving chromosomes and dna alteration and/or permanent dysfunction.
    that is our core, our foundation

    are any CFS genome studies published?
     
  2. SaveMe

    SaveMe *****

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    the city
    my wish came true :(

    A 2007 review stated that certain genetic polymorphisms might be regarded as predisposing factors. Studies have shown genetic differences in genes of CFS patients and healthy controls in the central nervous,endocrine,immune and cardiovascular systems.

    CFS-related abnormalities in gene expression have been studied. Changes in genes involved in transport (both vesicle-mediated and protein transport), metabolism, immune regulation, neuronal function, mitochondrial function, apoptosis and other processes have been reported.


    We are aliens, our DNA is damaged.

    Lets get down to the bottom of this, Go Big or Go Home. We don't have time to waste.
     
  3. kurt

    kurt Senior Member

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    USA.Earth
    I noticed in the current CAA call for research proposals they are asking for new genomic studies. Would be nice if we knew more about those abnormalities...
     
  4. SaveMe

    SaveMe *****

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    the city
    kurt, you stay on top of your research! you also have the methylation protocol right? I saved it somewhere.
     
  5. rwac

    rwac Senior Member

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    It might be mitochondrial dysfunction too.
     
  6. soxfan

    soxfan Senior Member

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    North Carolina
    My fatigue feels as though the life has drained out of me and I am left with just a shell of myself. I never have the sleepy or want to sleep fatigue. It has always been a total draining in which I have to lay down and rest..I am totally unable to fall asleep during the day. Maybe that would help if I could...
     

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