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other B cell depletors, far future

Discussion in 'Rituximab: News and Research' started by Sherlock, Sep 18, 2012.

  1. Sherlock

    Sherlock tart cherry etc. for joints, insomnia

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    Czechosherlockia, USA
    Clin Immunol. 2012 Mar;142(3):237-42. Epub 2012 Jan 5.
    Syk inhibition with fostamatinib leads to transitional B lymphocyte depletion.

    http://www.ncbi.nlm.nih.gov/pubmed/22284392

    Syk = spleen tyrosine kinase

    Now just for fun, imagine your own clinical trial.

    Syk inhibitors for sale:
    http://www.selleckbio.com/syk-inhibitors.html?gclid=CIiHgYLjtbICFcne4AodYSoAYQ

    Offhand, it seems that anybody with a credit card can buy it?


    This trial uses up to 200mg per day: http://www.clinicaltrials.gov/ct2/show/NCT01242514?term=oskira&rank=1

    Fostamatinib for sale:
    http://www.selleckbio.com/R935788-Fostamatinib-disodium-S2206.html

    So 200mg = a mere $5000
     
  2. taniaaust1

    taniaaust1

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    Sth Australia
    a mere $5000.. and just maybe I'll win the lotto one day.
     
  3. Sherlock

    Sherlock tart cherry etc. for joints, insomnia

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    Czechosherlockia, USA
    I looked for a price on the lab mice to go with the drug. Wow, there must be close to 100 strains under Immunology and Inflammation Research alone. It seems like fairly big business.

    [​IMG]
    Strain listing for Immunology and Inflammation Research

    The links below offer the most recent strain information for Immunology Models, including current ordering and pricing information:

    http://jaxmice.jax.org/list/rax10.html
     

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