I believe the findings from the study linked below are perfectly linked to the case of CFS: http://www.ncbi.nlm.nih.gov/m/pubmed/23268242/?i=2&from=herpes pharynx russian A common virus e.g the infamous EBV, combined with pathogenic bacteria e.g Streptococci equals viral persistence. Of course the study does not mention CFS specifically, as most studies of this kind do not. But the findings are of crucial importance for us. The study has focused on the viral-bacteria combo persistence in the pharynx, but of course this can occur in other parts of the body, e.g the human gut. This links with: -Lipkin, who says the action is in the gut (bacterial/viral) -KDM who found abnormally high levels of Strep and Entero bacteria in PWCFS. -Pridgen who has found evidence of HSV in patient guts -The familial connection as bacteria is passed to us from our mothers which is the way we are 'predisposed' to CFS. -Lerner who has for decades firmly believed in EBV causing CFS -VZK who theorised the vagus nerve -Loomis who believes in HHV6 Pathogenic Bacteria combined with A virus can lead to viral persistence and hence a chronic inflammatory state due to a chronically active immune system and hence the myriad of symptoms we call Chronic Fatigue Syndrome. I've been doing nothing but reading and experimenting for the last decade and have had CFS since age 4, this is by far the definitive cause of CFS for the very large majority of us. I am positive this cause can also manifest itself as other syndromes, FM etc.... Eagerly awaiting Pridgens results as he claims his combo of drugs stop the PROCESS which leads to symptoms, such as detaching the virus and bacteria which persists. This is the next best thing to a cure. To achieve a cure, the bacteria must also be eliminated in order to remove the predisposition that we inherited. I've focused on the bacterial side of this theory extensively in my thread for those interested: Http://forums.phoenixrising.me/index.php?threads/gut-microbes-pathogenesis-of-cfs.27546/ I am writing this rushed at work. So correct me on any mistakes and I'll edit. Jon.