Discussion in 'General ME/CFS News' started by mango, May 18, 2016.
Sounds good. Both the biomarker candidate, and the validation study being launched immediately.
Plenty of interesting and hopeful info in the newsletter!
Bring it on, Dr. Naviaux!
Imagine a treatment that just flips a switch, and boom, you're back to your old fully capable self! OMG!!!
Maybe i am just in denial, but i really believe it's possible. Natural remissions happen all the time, so the human body is capable of recovering from this.
I can barely dream of something like that!
Piece will be on #MEAction tomorrow AM. This is the best news we've had in a long while.
Did you guys see that someone donated nearly half a million dollars to fund this? One. Person. Or entity, but still. Whoever you are, thank you so much.
Seriously, gigantic thanks to whoever donated it!
LOLOL an organization! Not !
You never know! Could be a rich or anything!
I really feel like they should give us the first letter of the metabolite so we can have some fun guessing in the meantime.
It says "a chemical signature" so maybe it's more than one?
I've absolutely no idea what I'm talking about, though.
They definitely could have given us the first letter of one of them then.
No letters, damn it! We might wind up with an acronym...
I've read about Naviaux's cell danger response theory before but didn't realise that the mitochondria were so deeply implicated.
Didn't we play that game with the lipkin study - was that related to this in any way ?
Don't think it's related in any way - Lipkin / Hornig collaborate with the Simmaron Research Foundation, which is where Lipkin disclosed that they had evidence of altered levels of two metabolites and one immune protein. Will the OMF replicate the findings?
I recovered from my first 2 bouts (8 mos and then 2 months) of ME. This third bout has been almost 18 months, but I still believe (most days) that I will recover and get back to my life.
I've never heard that mitochondria were involved in cellular defense in any way, shape or form. I *taught* this, and while I went beyond "powerhouse of the cell" simplicity, I never had any idea that mitos did this.
Anyway, if one goes by the review article @Scarecrow links, Naviaux's premise is that the metabolites that are dysfunctional are 'p' for 'purines'... purine metabolism is wonky. Purines are adenine and guanine -- the adenine that's the 'a' in ATP.
Significant shifting of the layout, but no words were altered (maybe I removed an 'and'.)
(This is Figure 1.)
I'm tired, but I'm really sick tonight, so, yeah. I had the time to do this. <--- latter one is in my imagination.
You can also try a Google Site Search
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