I've been discussing Oil of Oregano with @ljimbo423, but also wanted to start a thread to glean some other experiences, given that I've read conflicting reports on its supposed safety. Some people claim it destroys beneficial flora, and I also read one guy here state that he believes it tipped his ME into the severe category. Has anyone else here tried it to treat SIBO? I'm about 5 days in and it makes me feel kinda off in a similar way to Flagyl .. just a little 'toxic', fuzzy-headed, very apathetic etc. I've put this down to herxing/die-off and am using coffee enemas to cope.