I decided to conduct a sort of experiment recently. I (like I'm sure all of us) am on a bunch of supplements but have never felt any noticeable difference from anything, so I decided to taper off everything to see if there's a difference. Here's what I currently take daily. High dose Phosphatidylcholine High dose Theracurmin Bicailin Valcyte LDN Vitamin D B12 Magnesium Tyler panplex digestive support Dr Enlanders electrolyte blend Dr Enlanders Hepapressin (once/week) Injectable b complex (once/week) I tapered off everything correctly and it's been about 1 month now and like I suspected- No difference whatsoever. My brain is still as bad as it was, my tolerance to energy expenditure hasn't changed and my muscle weakness/fatigue levels are the same When I first got adrenal fatigue a few years ago I saw slight changes depending on what supplements I took- now since ME there is nothing. It makes me think that my health problems are much more deeply rooted than any medicine can touch. In the interest of saving money, I'm staying off everything.