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"Normal" CD4/CD8 Ratios.

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by Ema, Feb 23, 2014.

  1. Ema

    Ema Senior Member

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    @Sea, @SOC,

    With all the talk of XMEN, I got curious what else was out there about "normal" ratios.

    Mostly, things talk about ratios lower than 1 in HIV infection being a bad sign.

    But I found some different things that I also found interesting...

    If you have a viral infection, your ratio may be decreased...but if you have an autoimmune condition, your ratio may be increased. Considering how often these go together in our population, one has to wonder how useful this measurement is AT ALL.

    If your ratio is above 2...does that REALLY mean your immune system is strong...or does it mean it is overreacting to everything...or you have a really terrible infection?

    No wonder other sites say this ratio has fallen out of favor. It seems to bring up more questions than it answers.

    FWIW, my ratio was 2.2 in 2010, prior to any treatment other than some vitamins etc and is 1.87 as of 11/13.



    http://www.aidsmap.com/CD4CD8-ratio/page/1733224/

    http://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=cd4_cd8_ratio

    heapsreal and Sea like this.

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