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Non-Infected Babies Born to HIV Mothers Have Reduced Immunity to Measles

Overstressed

Senior Member
Messages
406
Location
Belgium
ScienceDaily (Oct. 18, 2012) — Non-infected babies born to HIV positive mothers should be vaccinated early against measles, to avoid them acquiring the virus or passing it on to others.

A study published in the November issue of Acta Paediatrica found that even if babies are born without HIV, their maternally derived protection against measles may be impaired by their mother's positive HIV status.
(...)

The conclusion is interesting:
(...)
"This found statistically significant differences between the maternal antibodies received by the two sets of babies and showed that the non-infected babies born to HIV positive mothers had weaker protection. This was because the antibodies normally produced by the mother to help protect her baby from measles had lost their sharp edge due to her HIV positive status.
"The results suggest that babies born to HIV mothers would not be able to neutralise the measles virus as effectively and would loose protection sooner than babies born to healthy mothers. These babies would therefore be much more likely to succumb to measles and, or, pass the virus on to other children, making their early immunisation vital."


Please find the full article here:
http://www.sciencedaily.com/releases/2012/10/121018100121.htm

Best regards,
OS.
 

natasa778

Senior Member
Messages
1,774
Ops, but it never occurs to them that those babies might not be able to mount an effective response to vaccine strain measles virus, and so they end up with a chronic infection living in their guts or wherever forever after.

Duh!
 

natasa778

Senior Member
Messages
1,774
Most interesting here IMO that there is no mention that mothers had full blown AIDS, they were 'only' HIV positive. So their immune compromise is not severe or clinically obvious. In relation to autism it is now well established that there is something wrong with the immunity/inflammatory state of mothers, I wonder if the increased bacterial and viral presence in asd kids could be at least partially because of something like this (i'.e. not only because of their own immunity being impaired, but also their mothers, allowing for more early exposure/infections adding to the neurotoxic load).

Wondering if there is any data on immune states of mothers whose children later develop CFS?