I don't think this has been posted yet. Neurodegenerative and Fatiguing Illnesses, Infections and Mitochondrial Dysfunction: Use of Natural Supplements to Improve Mitochondrial Function. Garth L. Nicolson, Robert Settineri and Rita R. Ellithorpe Functional Foods in Health and Disease 2014; 4(1):23-65 Publication date: January 25, 2014 Full paper available here: http://functionalfoodscenter.net/files/81845995.pdf This paper is a review of various studies that have tested health supplements for a variety of fatiguing illnesses, including CFS. There are a grand total of 319 references in this paper! A special Phoenix Rising prize goes to the first person who reads them all! The review suggests that there have been substantial reductions in fatigue in CFS patients after some of these supplements were prescribed. But the devil is in the detail i.e. the methodology of the reviewed papers. i.e. were there control groups? I've only checked one of the reviewed papers (see next post), which does not have a control group, but I suspect that they are mostly, or entirely, low-powered and without an adequate control group.