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Niacin - Why am I not flushing??

Discussion in 'Mast Cell Disorders/Mastocytosis' started by Ema, Oct 10, 2013.

  1. Ema

    Ema Senior Member

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    Midwest USA
    I decided to experiment today with niacin.

    I had read that one should start with 50 mg and then wait to see if flushing occurred. If so, it indicates high histamine. If it takes 100 mg to flush, then that indicates normal histamine levels. 150-250 mg indicates low histamine levels.

    So I took 50 mg...nothing. And then another 50 mg. Still no flush!

    I'm so confused because I always thought I had high histamine based on my reactivity and whole blood histamine levels.

    Then I read that some of the orthomolecular doctors like Abraham Hoffer say that you won't flush if you have a niacin deficiency.

    They suggest taking 1000-3000 mg of niacin 1-3x/day which is obviously a much higher dose than the 100 mg I took.

    Any ideas about this? I had really hoped that niacin would help my migraine headaches.

    http://www.nutritionj.com/content/4/1/3

    I'm also curious about the relationship of nicotine to niacin...is there one? Does nicotine metabolize into niacin?

    Thanks for any insights into this!

    Ema
  2. Sparrow

    Sparrow Senior Member

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    Canada
    Just to confirm, are you taking plain old niacin (not niacinamide, nicotinamide, nicotinic acid amide, inositol hexaniacinate or what have you)?
    Sparrowhawk likes this.
  3. Ema

    Ema Senior Member

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    Midwest USA
    Yes, it even says on the bottle that it can cause a "totally normal" flushing reaction!
  4. camas

    camas Senior Member

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    Ema

    I hope someone can solve this mystery for you. I hadn't heard of niacin reducing histamine levels. I may have to give this a try. Thanks! :)

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