Completely agree. Please be gentle, I'm a newbie posting in the the grown-up forums. I've been looking hard for alternate explanations, that fit with what I know about myself and family. The one thing I thought I might've found, which is still crap, is Fragile-X, but I would not be totally shocked if Fragile-X turns out to be the work of XMRV. & Fragile-X dos'nt fit as well as XMRV unless I could have both Fragile-X and XAND, again my question would be does fragile-X increase your chances of having XAND. A gene marker was mentioned in Kerrs 80 gene study, that is a Fragile-X marker. But I cant understand the paper to see if it's showing a normal marker and others. Or if it showing up regulated , or down regulated. I could be completely off the ball. I f any one reads this, and can read understand Kerrs 80 Gene science paper, could they have a look at NUFIP2 it's listed in the tables and aon the gene card thingy. But again I have no idea if it's existence in the paper, is linking a marker for Fragile-X and CFS/ME XMRV XAND. Any help would be much appreciated. Thank you for trying to understand what I'm asking for here. I'm not sure I do.