News of replication of WPI XMRV study...

XMRV certainly could explain many things, including stress intolerance and Post Exertional Malaise

Sometimes my earliest symptom when starting into a flare-up, is to begin voiding (pee) off more fluids than I had taken in over the prior several days. It's a lot and happens fast....sure sounds HPA to me

tina hypothesis 2

Hi Tina, I like your hypothesis.

I am wondering if that is what is going on with me while I am taking Low Dose Naltrexone (LDN). I had the most amazing energy for the first two days. After those days I was back to my normal CFS energy for about a week and then felt terrible for another week.

I then took a week off of the LDN and started again. I had one good day and felt awful with depression and high anxiety (very unusual for me) after that. I have been trying a very low dose every 4 days and am still feeling terrible. In fact I think this is the worst I have felt with this illness in the 13 years that I have had it.

I wonder if the LDN is kicking up my immune system and I am paying for it. Also, I wonder if I will eventually be able to feel better on the LDN in I just wait out these negative effects?

Lynn

Crazy thought here...


Take an immunosuppressant with beneficial medications that over-stimulate the immune system.


I know it goes against what we think is good but it might work under some circumstances. Of course, under the supervision of a skilled immunologist.

Thoughts ?

Two Spin off Threads

I started a thread on the Push-Crash phenomena Ross and I were talking about

http://forums.aboutmecfs.org/showthread.php?p=19976#post19976

and I was so taken by Duedeni's post on exercise that I started one on our Reaction to Exercise.

http://forums.aboutmecfs.org/showthread.php?p=19973#post19973

duendeni

Your description of what I, too, experience is excellent. I need to print it out and show it to the next person who asks me how it feels, when I am so weak and sick I can hardly think or speak.

My one description of the heaviness of the fatigue, that some people have been able to grasp, is that it feels like the normal 1 gee of gravity here on Earth has changed to 3 Gs of gravity, or like I'm wearing magnetic boots and walking on an iron surface. I often stub my toes, thinking my feet are higher above the ground than they really are.