My take on this is that they backing way off the PCR test. I don't know how else to read it. Culture In/PCR Out - Oddly enough, they said that the culture test is "the only scientifically validated methodology to find XMRV" which puts into question the validity of the PCR test. In fact, the message indicates the WPI is backing away from the PCR test, heretofore, the main focus of validation efforts, stating "At this time no single PCR or whole blood assay alone has been validated as accurately detecting XMRV, and is therefore not an appropriate way to study or diagnose the presence of the virus." This means that your PCR tests, while certainly not meaningless, are not diagnostic yet. This is quite a change. XMRV is a new bug whose genetic variation from place to place is unknown; until more is known regarding how XMRV differs from location to location its going to be impossible to create a 'validated' test for it. The DHHS in cooperation with several labs is reportedly doing the work.