Hi, amazing and sometimes overwhelming information on this site. I've been on 75mg levothyroxine for the last 9 or so years. I'm guessing this might have been triggered by the sero-negative arthritis that started about 15 years ago. The arthritis was active for many years before going into remission. I was living with constant pain and inflammation for a long time, refusing to take medication such as methotrexate and sulphasazaline. A few years ago a suffered from a period of severe anxiety and sometimes panic but slowly managed to recover. These symptoms returned about three months ago but I've managed to slowly recover by about 70% by exercise, taking insositol, aswagandha, NAC, selenium, sublingual B12, 5HTP amongst others. Three days ago I started taking Jarrow Formulas, B-Right but after doing some reading am wondering if I might making some mistakes with my supplementation, especially after reading the 'Methylfolate side effects what happened' thread on this site. I appreciate this is a ME/CFS forum (I think I have a moderate form of CFS, or could it just be the effects of the arthritis?), but I would really appreciate any guidance on whether my combination of supplements are okay. I did read on one of the threads that there might be some issues with taking NAC and folate at the same time. My goal is to alleviate my symptoms of anxiety, brain fog, poor memory and eyesight getting worse. I really would love to improve my memory and cognitive ability.