Dr Mikovits said at the IiME conference in London that HTLV is the virus to think about rather then HIV. With HTLV she said that the virus could be sequenced from the same patient 40 years later and it would be the same. Also remember Dr Magiorkinis in the Lancet (start) Once a virus is endogenised, it is forced to follow the evolutionary rate of the host. Since XMRV is integrated in cell-lines the virus evolution is restricted to the host's pace of evolution, and viral descendants have none or minimum sequence diversity. Thus, if a contaminated product, previously cultured in cell-lines, is administered to people then the infections would provide the evolutionary patterns reported by Hue and colleagues.4 If the immunological data reported by Lombardi and colleagues5 are correct, then we need to trace the common source for these infections to prevent possible public health concerns. Products from cell-lines should be the first candidates.