Hi people with POTS and OI, This is new to me... Have an appt. to see Dr. Klimas in June. Her assistant sent a bunch of paperwork. Part of it gives instructions to measure BP and heart rate upon waking in the A.M., then measuring ten minutes later after being up and moving around. I bought a BP/heart rate cuff, and thought this would just be to fill out the paperwork. Found that my heart rate is about 80 in bed and after ten minutes goes up to between 140-160. It stays around 110 when sitting with my feet up. Is this fairly standard for most with CFS and POTS? Have had CFS since 85, but have been declining the past five years, and now am wondering if this might be why. Did you have POTS onset at the same time as when you were diagnosed with CFS, or after...or before? Do you feel like having POTS affects your cognitive state, or mostly fatigue? Do most people here choose to medicate the symptoms with pharmeceuticals? Any tips that help you? Thank you for your help!