Does this stuff last without increasing the dosage? In my particular case, I have a pretty long history of trying things (drugs, supplements, activities) that work for just a couple days and fizzle out. I've given up on some things, and in other cases stayed faithful for many months, but there is ultimately no difference. The only thing that has consistently helped me out as of late is fasting throughout the day, eating no more than 50 calories an hour. After 15 years of trying things, LDN initially seems like a breath of fresh air. Only learned of it a couple weeks ago. However, it sounds like any other drug I've taken... It makes you high by releasing endorphins by doing something chemically to keep the endorphins in your system. Do this over and over again and the body compensates by shutting things off. For me, within a couple days. I can't imagine this would be any different? Also, is it really all that hard to get this stuff prescribed? Do I really have to see a specialist that is listed on the Internet? I'm sure I could get the folks at my local sleep disorders clinic to prescribe this? Or any physician?