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New Study Shows Vaccines Cause Brain Changes Found in Autism

Discussion in 'Other Health News and Research' started by Rosemary, Jul 17, 2010.

  1. Rosemary

    Rosemary Senior Member

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    http://www.ageofautism.com/2010/07/new-study-shows-vaccines-cause-brain-changes-found-in-autism.html
    By Dan Olmsted and Mark Blaxill

    Abnormal brain growth and function are features of autism, an increasingly common developmental disorder that now affects 1 in 60 boys in the US. Now researchers from the University of Pittsburgh and Thoughtful House Center for Children in Austin, Texas, have found remarkably similar brain changes to those seen in autism in infant monkeys receiving the vaccine schedule used in the 1990s that contained the mercury-based preservative thimerosal.

    The groups findings were published yesterday in the journal Acta Neurobiologiae Experimentalis. They used scanning techniques that assessed both brain growth and brain function in the same animals over time. The research team was able to see differences in the way the brains of vaccinated and unvaccinated animals developed. Scans were performed before and after the administration of primary MMR and DTaP/Hib boosters that were given at the human equivalent of 12 months of age.

    Throughout the study period, vaccinated animals showed an increase in total brain volume a feature of the brain in many young children with autism - when compared with unvaccinated animals. However, a specific part of the brain associated with emotional responses that is thought to be important in autism, the amygdala, did not show abnormalities until after the 12-month vaccines had been given. In addition, after the 12-month vaccines only, the functional brain scans showed significant differences between vaccinated and unvaccinated groups. These functional scans looked at the activity of receptors for morphine-like compounds (opioids) that may play a role in the brain of children affected by autism. Vaccine administration was associated with an increase in opioid binding activity in the amygdala compared with a decrease in the unvaccinated group.

    The results indicate that multiple vaccine exposures during the previous 3-4 months may have had a significant impact on brain growth and development in ways that are consistent with the published data on autism. For the amygdala, the novel findings of abnormal growth and function appear to be a function of more recent vaccine exposures - the 12-month primary MMR vaccine and the DTaP and Hib boosters.

    In an accompanying editorial Dr. Kris Turlejski, the Editor-in-Chief, described the findings as alarming, support[ing] the possibility that there is a link between early immunization and the etiology of autism.

    In the same primate model, the research team has already identified delayed acquisition of vital brainstem reflexes in infants exposed to the thimerosal-containing hepatitis B vaccine on the first day of life, compared with unvaccinated animals. A larger, second phase study is currently underway to see if these findings can be replicated.

    Dr. Andrew Wakefield, who is not a listed author but whose support in the design of the study is acknowledged, said I hope the model will not only provide important insights into the origins of autism, but also ways of safely testing possible new autism treatments and vaccines.

    References:
    Laura Hewitson, Brian J. Lopresti, Carol Stott, N. Scott Mason, and Jaime Tomko. Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study. Acta Neurobiol Exp 2010. 70: 147164

    Kris Turlejski. Focus on Autism Editorial Comment Acta Neurobiol Exp 2010. 70: 117118
  2. Rosemary

    Rosemary Senior Member

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    http://www.ane.pl/showarticle.php?art=7020

    Acta Neurobiologiae Experimentalis

    Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study

    Hewitson L.*1,2, Lopresti B.3, Stott C.4, Mason N.S.3, Tomko J.1

    1Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; *Email: lch1@pitt.edu 2Thoughtful House Center for Children, Austin, TX, USA; 3Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 4Independent Chartered Scientist, Cambridge, UK;

    Abstract. This longitudinal, case-control pilot study examined amygdala growth in rhesus macaque infants receiving the complete US childhood vaccine schedule (1994-1999). Longitudinal structural and functional neuroimaging was undertaken to examine central effects of the vaccine regimen on the developing brain. Vaccine-exposed and saline-injected control infants underwent MRI and PET imaging at approximately 4 and 6 months of age, representing two specific timeframes within the vaccination schedule. Volumetric analyses showed that exposed animals did not undergo the maturational changes over time in amygdala volume that was observed in unexposed animals. After controlling for left amygdala volume, the binding of the opioid antagonist [11C]diprenorphine (DPN) in exposed animals remained relatively constant over time, compared with unexposed animals, in which a significant decrease in [11C]DPN binding occurred. These results suggest that maturational changes in amygdala volume and the binding capacity of [11C]DPN in the amygdala was significantly altered in infant macaques receiving the vaccine schedule. The macaque infant is a relevant animal model in which to investigate specific environmental exposures and structural/functional neuroimaging during neurodevelopment.
    Keywords: rhesus macaques, Macaca mulatta, non-human primates, animal model, neuroimaging, PET, MRI, amygdala, opioids, ethyl mercury, thimerosal, eurotoxicity

    Link to full pdf file: http://www.ane.pl/showarticle.php?art=7020
  3. jewel

    jewel Senior Member

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    Thank you for posting this!
  4. xrayspex

    xrayspex Senior Member

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    u.s.a.
    Have you looked into the vaccine info related to HIV? Seems like that research could have clues for autism and cfs and everything else too...

    Current methods of growing the Sabin poliovirus vaccine "eliminate most of the blood and lymphocytes" known to be susceptible to the AIDS viruses, Quinnan tells me. Preparations are monitored, and that "provides assurance that there is freedom from most agents," he says. As for being sure the stuff is free from all agents, like some new retrovirus we don't yet know about, Quinnan says: "No, you can never prove something absolutely. However, as far as we know, the system we use doesn't result in any extraneous viruses."

    Like Salk and Sabin, Koprowski had the best intentions: He wanted to eradicate a debilitating and deadly scourge. But with what we know now, it's clear there was a certain hubris involved in the rough-and-ready campaigns to conquer polio. There is evidence that all three pioneers used vaccines inadvertently contaminated with viruses from a species dangerously close to our own. If the Congo vaccine turns out not to be the way AIDS got started in people, it will be because medicine was lucky, not because it was infallible.

    from:
    The origin of Aids by Tom Curtis

    http://www.whale.to/vaccines/curtis.htm

    and the book The River by Hooper goes further, I dont know what the update is...sure don't hear much about it do ya

    http://www.bmartin.cc/dissent/documents/AIDS/River/Hooper_00/

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