Invisible Illness Awareness Week 2016: Our Voices Need to Be Heard
Never heard of Invisible Illness Awareness Week? You're not alone. Jody Smith sheds a little light to make it more visible
Discuss the article on the Forums.

New study showing how LPS triggers immune response

Discussion in 'Other Health News and Research' started by Effi, Jul 4, 2016.

  1. Effi

    Effi Senior Member

    Messages:
    1,491
    Likes:
    4,552
    Europe
    http://www.jbc.org/content/early/2016/06/29/jbc.M116.741256
    Dectin-2 recognises mannosylated O-antigens of human opportunistic pathogens and augments lipopolysaccharide activation of myeloid cells
    1. Alexandra Wittmann1,
    2. Dimitra Lamprinaki1,
    3. Kristian M. Bowles2,
    4. Ewa Katzenellenbogen3,
    5. Yuriy A. Knirel4,
    6. Chris Whitfield5,
    7. Takashi Nishimura6,
    8. Naoki Matsumoto6,
    9. Kazuo Yamamoto6,
    10. Yoichiro Iwakura7,
    11. Shinobu Saijo8 and
    12. Norihito Kawasaki1*
    First Published on June 29, 2016
    doi: 10.1074/jbc.M116.741256jbc.M116.741256.

    Article on the paper: http://www.ifr.ac.uk/news/latest-news/2016/07/new-insights-how-we-fight-bacterial-infection/
     
    Justin30, alkt, rosie26 and 7 others like this.
  2. Groggy Doggy

    Groggy Doggy Senior Member

    Messages:
    1,127
    Likes:
    4,132
    "Whilst the lipid part is relatively similar between different bacteria, the polysaccharide is highly variable"

    @Effi I like this research, a true international effort. It's very interesing and I hope future research will reveal what causes the variability.
     
    Justin30, alkt and Effi like this.
  3. Justin30

    Justin30 Senior Member

    Messages:
    1,065
    Likes:
    1,280
    It would be be very beneficial for a standardized test to show the amount of LPS in blood serum.

    This being said CD14 is a marker for LPS but is not readily used.

    Further drugs that are safer in the reduction of LPS in serum need to be developed to tackle this problem as LPS seems to interefere with many biological process such as the breakdown of vitamins, minerals and amino acids.
     

See more popular forum discussions.

Share This Page