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New study - 8 SNPS corresponding to CFS/ME symptoms

Discussion in 'Genetic Testing and SNPs' started by Mary, Jan 23, 2016.

  1. Mary

    Mary Senior Member

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  2. adreno

    adreno PR activist

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    That's weird. I'm an exact match with the author. And I'm haplogroup H.
     
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  3. John Mac

    John Mac Senior Member

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  4. Mary

    Mary Senior Member

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  5. Mary

    Mary Senior Member

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    I'm almost an exact match and am haplo group V.
     
  6. adreno

    adreno PR activist

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    @Valentijn would you be interested in taking a look at this?
     
  7. Valentijn

    Valentijn Senior Member

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    MTDNA, especially the parts discussed in the recent research paper, is pretty much identical for everyone with the same haplogroup. Similarities simply mean that everyone is of European extraction in their maternal line. We don't have any increase in rare haplogroups, and when matched with controls from the same haplogroups our MTDNA SNPs are pretty much entirely identical.

    Also, for many of the SNPs, it's the more common allele which was found to be associated with the more severe symptoms in some categories. So it's to be expected that a lot of ME/CFS patients would have both those symptoms and those alleles.

    Beyond that, I'm not sure what you'd want me to look for. There might be ways to "help out" genes with presumed dysfunctional SNPs on them, but that's going to vary depending on which genes are involved for each person.
     
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  8. Ellkaye

    Ellkaye

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    Can this be used for improved/'cured' patients?
     
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