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New "Pill Form" MS Treatments Debut

Discussion in 'Other Health News and Research' started by Gemini, Nov 21, 2012.

  1. Gemini

    Gemini Senior Member

    Wall Street Journal, November 20, 2012, "As MS Pills Debut, Doctors Prescribe a Dose of Caution"

    Newest pill, Aubagio, another called BG-12 in the pipeline, join Gilenya which was approved in 2010.

    Excerpts of interest to ME/CFS:
    "Reseachers say multiple sclerosis wreaks havoc with a patient's immune system, causing it to damage healthy nerves and the myelin sheaths that wrap around nerve fibers, disrupting signals from the brain. Researchers still don't understand why the immmune system goes haywire.
    They believe it is a combination of genetic and environmental factors, including exposure to a virus."

    "It is difficult to find multiple sclerosis treatments that are both effective and safe, experts say, because the understanding of the disease continues to evolve."
    MishMash, beaker and Merry like this.
  2. MishMash

    MishMash *****

    BG-12 is the only drug in the pipeline that gives me any hope. It is an MS drug that may have wide implications for many unexplained autoimmune illnesses. Including ours.

    It is based on the theory of oxidative stress and glutathione defiency, most prominently developed and espoused by our late, great benefactor Dr. Rich Van Kronynberg. The drug is based on a commonly used anti-psoriasis drug, still prescribed in Europe. So it has the distinction of *having actually worked as an anti-inflammatory in other conditions*. In an age when pharma companies produce more placebo snake oil than effective drugs, this is a big deal.

    Add to that, the maker Biogen, spent hundreds of millions to test and re-test, and found actual, concrete benefits for the patients. I don't trust most drug company results, because they have such a huge, compelling profit motive to say something "works" when it is doesn't. But in the case, there seems to be some overlapping circumstantial evidence. I'm sure it will be extremely expensive, but at least it does not involve self-injecting.
    Sasha likes this.
  3. Marco

    Marco Old blackguard

    Near Cognac, France
    merylg, Emootje and MishMash like this.
  4. Gemini

    Gemini Senior Member

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