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Can You Come for a Visit? My ME/CFS Says No
My daughter and son-in-law just had a baby last week. We are thrilled. But we won't be able to see the baby or hold her any time soon. We won't be able to take over little gifts or help out with housework or babysitting.
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New Lyme test

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by maryb, Jun 5, 2014.

  1. maryb

    maryb iherb code TAK122

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    John Mac, beaverfury and Helen like this.
  2. Helen

    Helen Senior Member

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    But it can´t differ between an ongoing infection or a past one with only one test. Still worth looking at this instructive video
  3. maryb

    maryb iherb code TAK122

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    @Helen
    sorry Helen not up to watching that video, too much head pressure.
    Do you mean it can't distinguish between an ongoing infection or one that has been treated successfully?
  4. Helen

    Helen Senior Member

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    I don´t have that answer for sure, but at least just one test will not tell if it is an ongoing infection or one that has been cured by itself (or with antibiotics I suppose). I do hope your head pressure will be over asap.
    maryb likes this.
  5. maryb

    maryb iherb code TAK122

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    @Helen
    thanks - me too..
  6. lazzlazz

    lazzlazz

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    I saw this article http://abcnews.go.com/Health/mans-ravaging-lyme-disease-eludes-doctors-year/story?id=24341585
    about the American musician who got lyme in Spain (and saw the tick and had EM rash) & then it took American physicians a year to diagnose it, because the American tests don't test for European ticks. Apparently, the European test tests for 18 species.
    "Bargfrede had a C6-based ELISA test, which is widely used in Europe and can detect as many as 18 species of the Borrelia bacterium. But the test is not used in the U.S., according to the CDC."

    I started looking on google to see whether that European test - or something similar - is available in the US. Immunetics has a C6-based ELISA test but it seems that it tests for fewer species (I don't have any expertise in this area - I'm assuming that "C6-based ELISA" means that the Immunetics test and the European test use the same process, but test for different species. I could be wrong.)

    Immunetics claims 99% specificity for their test, and claims that their test is superior to the CDC recommended tests. The website says the test is FDA approved. I'm not sure what the politics are regarding the CDC recommended 2-test procedure vs. Immunetics. I tried to figure this out; it wasn't really clear but there may have been some results that showed Immunetics test as being just slightly worse, at the tine the decision was made. (Of course, Immunetics wouldn't try to overstate their results!) If anyone has any info, please reply.

    http://www.immunetics.com/lyme.html
    Lyme disease can be difficult to diagnose. Traditional Lyme ELISA tests are short on specificity and can generate over 20 percent false positive results. This uncertain performance can result in time-consuming, expensive Western Blot confirmatory tests. The C6 Lyme ELISA from Immunetics sets a new standard in Lyme test accuracy, and delivers more reliable results sooner and more economically than any other ELISA. It demonstrates 99 percent specificity in an average population – equivalent to the specificity of Western Blot testing and a 10-fold improvement over Whole Cell Sonicate ELISAs. Additionally, the C6 Lyme ELISA is a far more sensitive assay – showing twice the sensitivity of the standard Western Blot in patients with symptoms of acute or early Lyme disease. These features mean that more patients are correctly detected as positive for the disease. From early onset to late stage disseminated infection, C6 Lyme ELISA demonstrates superior results.
    • Accurate: Western Blot accuracy in an ELISA
    • Sensitive: More sensitive detection of antibodies in early and late Lyme disease than competing kits
    • Specific: Eliminates vast majority of other ELISA's false positives at the screening step
    • Broadly applicable: Detects infection with all strains of Borrelia which cause Lyme disease, including European strains B. garinii and B. afzelii.
    • Convenient: One hour turnaround time, breakaway strips for any number of samples, ready-to-use reagents and controls included
    • Cost-effective: Greatly reduces the number of samples sent for expensive and lengthy confirmatory testing
    Last edited: Jul 29, 2014
    Valentijn likes this.
  7. Helen

    Helen Senior Member

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    Isn´t an EM rash a definite Lyme diagnose everywhere? I thought it was a consensus about this if there is, or has been, an EM rash. In Northern Europe there is no claim for testing if EM is present.
    PennyIA likes this.
  8. fibrodude84

    fibrodude84

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    Is this test in use yet? It still can prove a definite non diagnosis if someone never was infected and can rule out lyme.

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